Jürgen Rehm 2024

A Study Examining Efficacy and Cost-Effectiveness of Thai Medical Cannabis Products in Increasing Quality of Life of End-Stage Cancer Patients Receiving Palliative Care

Bundit Sornpaisarn, Nisachol Dejkriengkraikul, Weena Thitipraserth, Waranist Lamyai, Namfon Sribundit, Phaviga Thangsuk, Busaya Santisant, Valika Ratanachun, Watcharapong Rintara, Kanin Longseng, Nattiya Kapol, Surasit Lochidamnuay, Wanrudee Isaranuwatchai, Kanitta Bundhamcharoen, Thitiporn Sukaew, Jürgen Rehm

This study aimed to examine the efficacy and cost-effectiveness of two Thai tetrahydrocannabinol
(THC)-prominent cannabis products in improving the quality of life for end-stage cancer patients receiving
palliative care. This study was conducted as a randomized, double-blind, four-arm parallel-group…

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Substance use as a public health issue: A critical review of the Canadian literature, 1896–2020

Jean-François Crépault, Brian Emerson, Elaine Hyshka, Carol Strike, Robin Room, Jürgen Rehm

The risks associated with substance use can be framed in many ways. In Canada, the consumption of psychoactive substances has at various times been considered a moral, criminal, or medical issue. In the past decade, substance use has increasingly been framed as a public health issue. This study sought to trace the historical development and evolution…

The role of alcohol control policies in the reversal of alcohol consumption levels and resulting attributable harms in China

Jürgen Rehm, Kevin Shield, Ahmed Hassan, Ari Franklin

Yearly adult per capita consumption of alcohol in China between 2016 and 2019 decreased by 2.4 L of pure alcohol, or 33%. According to the World Health Organization, this decrease in consumption was accompanied by reductions in alcohol-attributable mortality of 23% between 2015…

Alcoholic beverage consumption and female breast cancer risk: A systematic review and meta-analysis of prospective cohort studies

Ivneet Sohi, Jürgen Rehm, Marian Saab, Lavanya Virmani, Ari Franklin, Gonzalo Sánchez, Mihojana Jhumi, Ahmed Irshad, Hiya Shah, Daniela Correia, Pietro Ferrari, Carina Ferreira-Borges, Beatrice Lauby-Secretan, Gauden Galea, Susan Gapstur, Maria Neufeld, Harriet Rumgay, Isabelle Soerjomataram, Kevin Shield

Alcohol consumption is an established cause of female breast cancer. This systematic review examines in detail the association between alcohol and female breast cancer overall and among the described subgroups, using all of the evidence to date…

Trends in alcohol-attributable morbidity and mortality in Germany from 2000 to 2021: A modelling study

Ludwig Kraus, Justin Möckl, Jakob Manthey, Pol Rovira, Sally Olderbak, Jürgen Rehm

We aimed to assess: (i) trends in alcohol-specific — that is, fully attributable — morbidity and mortality in the German adult population aged 15–69 between 2000 and 2021; and (ii) changes in alcohol-attributable disease burden — that is, fully and partially alcohol-attributable categories — for 2006, 2012, 2018 and…

The Lancet Public Health Commission on gambling

The global gambling industry is rapidly expanding, with net losses by consumers projected to reach nearly US$700 billion by 2028. Industry growth is fuelled by the rise of online gambling, widespread accessibility of gambling opportunities through mobile phones, increased legalisation, and the introduction of commercial gambling to new areas. Recent expansion is most notable in low-income and middle-income countries, where regulatory…

Trends in drug overdose deaths among adults 65 years of age and older in Canada (2000–2022)

Sameer Imtiaz, Farihah Ali, Nat Kaminski, Cayley Russell, Jürgen Rehm

Although young adults and middle-aged adults have borne the brunt of the drug overdose crisis in Canada, older adults are also at an increased risk of harms. We examined trends in drug overdose deaths and opioid overdose deaths…

Classifying national drinking patterns in Europe between 2000 and 2019: A clustering approach using comparable exposure data

Daniela Correia, Jakob Manthey, Maria Neufeld, Carina Ferreira-Borges, Aleksandra Olsen, Kevin Shield, Jürgen Rehm

Previously identified national drinking patterns in Europe lack comparability and might be no longer be valid due to changes in economic conditions…

Forecasting the impact of means restriction on the suicide mortality rate in the Region of the Americas: an ecological modeling study

Shannon Lange, Kawon Kim, Huan Jiang, Kevin Shield, Jürgen Rehm, Anselm Hennis, Renato Oliveira e Souza

It was estimated that if a firearm or pesticide restriction had been implemented in 2020 in those countries where the respective means accounted for 40% or more of all suicides for at least one sex in 2019…

Changes in medical cannabis use in Ontario, Canada (2014 to 2019): Trajectory of trends, medical authorization patterns and association with recreational cannabis legalization

Sameer Imtiaz, Yeshambel Nigatu, Farihah Ali, Tara Elton-Marshall, Jürgen Rehm, Sergio Rueda, Hayley Hamilton

We characterized trends in medical cannabis use; examined characteristics associated with medical cannabis use without…

The prevalence of gambling and problematic gambling: a systematic review and meta-analysis

Lucy Tran, Heather Wardle, Samantha Colledge-Frisby, Sophia Taylor, Michelle Lynch, Jürgen Rehm, Rachel Volberg, Virve Marionneau, Shekhar Saxena, Christopher Bunn, Michael Farrell, Louisa Degenhardt

Gambling behaviours have become of increased public health interest, but data on prevalence remain scarce. In this study, we aimed to estimate for adults and adolescents the…

Priorities for addressing adolescent cannabis consumption following non-medical cannabis legalization in Canada

Sameer Imtiaz, Tara Elton-Marshall, Hayley Hamilton, Sergio Rueda, Jürgen Rehm

We want to emphasize that measures addressing high-risk cannabis use should be prioritized. Pertinently, comparative risk assessments have underscored that the cannabis-attributable burden of disease primarily stems from high-risk cannabis use in the…

Alcohol rehabilitation and cancer risk: a nationwide hospital cohort study in France

Michaël Schwarzinger, Carina Ferreira-Borges, Maria Neufeld, François Alla, Jürgen Rehm

Even though alcohol consumption is an established risk factor for cancer, evidence regarding the effect of a reduction or cessation of alcohol…

Effect of alcohol health warning labels on knowledge related to the ill effects of alcohol on cancer risk and their public perceptions in 14 European countries: an online survey experiment

Daniela Correia, Daša Kokole, Jürgen Rehm, Alexander Tran, Carina Ferreira-Borges, Gauden Galea, Tiina Likki, Aleksandra Olsen, Maria Neufeld

Alcohol health-warning labels are a policy option that can contribute to the reduction of alcohol-related harms, but their effects and public perception depend on their content…

A dose-response meta-analysis on the relationship between average amount of alcohol consumed and death by suicide

Shannon Lange, Laura Llamosas-Falcón, Kawon Kim, Aurélie Lasserre, Heather Orpana, Courtney Bagge, Michael Roerecke, Jürgen Rehm, Charlotte Probst

This is the first evidence synthesis on the dose-response relationship between average alcohol consumption and death by suicide.

Germany's cannabis act: a catalyst for European drug policy reform?

Jakob Manthey, Jürgen Rehm, Uwe Verthein

With the enforcement of the Cannabis Act on 1 April 2024, Germany has adopted one of the most liberal legal approaches to cannabis on the continent. The German model prioritises a non-profit approach and precludes legal market mechanisms. We believe these are the main drivers for increasing cannabis…

Covid-19, the polarization of substance use, and mental health

Jürgen Rehm

What does polarization mean and how can it be explained? First of all, economic crises or natural catastrophes lead to a reduction in availability and/or affordability of substances. In the case of COVID-19, lockdowns, restaurant and bar closures, disruptions of the supply…

Impact of alcohol use on liver disease outcomes

Hailemichael Desalegn, Luis Antonio Diaz, Jürgen Rehm, Juan Pablo Arab

Alcohol-associated liver disease (ALD) is a well-recognized consequence of heavy alcohol consumption. ALD develops in a dose-dependent manner and has a higher incidence in individuals exhibiting a more

Designing and implementing an experimental survey on knowledge and perceptions about alcohol warning labels

Daniela Correia, Alexander Tran, Daša Kokole, Maria Neufeld, Aleksandra Olsen, Tiina Likki, Carina Ferreira-Borges, Jürgen Rehm

This paper describes the design and implementation of an online survey experiment to investigate the effects of alcohol warning labels on alcohol-related knowledge, risk perceptions and intentions…

Rescheduling alcohol marketing bans within the World Health Organization menu of policy options

Hailemichael Desalegn, Luis Antonio Diaz, Jürgen Rehm, Juan Pablo Arab

LETTER TO THE EDITOR

Does higher alcohol consumption affect attitudes towards alcohol control measures in Estonia?

Rainer Reile, Jürgen Rehm

Alcohol policy is paramount in reducing alcohol-related harms. Making alcohol more expensive via taxation, restricting the physical availability of alcoholic beverages and limiting the exposure to alcohol advertising are examples of policies that have prove…

Quantifying alcohol-attributable disability-adjusted life years to others than the drinker in Aotearoa/New Zealand: A modelling study based on administrative data

Created by Sally Casswell, Taisia Huckle, Jose Romeo, Helen Moewaka Barnes, Jennie Connor, Jürgen Rehm

Quantifying the health burden of alcohol has largely focused upon harm to drinkers, which is an underestimate. There is a growing literature on alcohol‘s harm to others (HTO), but it lacks…

Relationship Between Alcohol Use and Firearm-Involved Suicide: Findings From the National Violent Death Reporting System, 2003–2020

Kawon Kim, Jürgen Rehm, Mark Kaplan, Shannon Lange

Acute alcohol intoxication is a contributing factor in firearm-involved suicides. However, knowledge of the relationship between alcohol intoxication and firearm-involved suicide by age and sex (defined herein as the biological sex of the decedent) is limited. The purpose of the current study was to evaluate the sex- and age group-specific relationship between…

Restricting alcohol marketing to reduce alcohol consumption: A systematic review of the empirical evidence for one of the ‘best buys’

Created by Jakob Manthey, Britta Jacobsen, Sinja Klinger, Bernd Schulte, Jürgen Rehm

Even though a ban of alcohol marketing has been declared a ‘best buy’ of alcohol control policy, comprehensive systematic reviews on its effectiveness to reduce consumption are lacking…

National and regional prevalence of interpersonal violence from others’ alcohol use: a systematic review and modelling study

Carolin Kilian, Sinja Klinger, Jakob Manthey, Jürgen Rehm, Taisia Huckle, Charlotte Probst

While alcohol use is an established risk factor for interpersonal violence, the extent to which people are affected by interpersonal violence from others’ drinking has not yet been quantified for different world regions. This modelling study aims to…

Alcoholic beverage types consumed by population subgroups in the United States: Implications for alcohol policy to address health disparities

Won Kim Cook, William Kerr, Yachen Zhu, Sophie Bright, Charlotte Buckley, Carolin Kilian, Aurelie Lasserre, Laura Llamosas-Falcón, Nina Mulia, Jürgen Rehm, Charlotte Probst

Individuals with low socio-economic status, racial/ethnic minority status or high drinking level prefer liquor and beer. As alcohol taxes, sales and marketing practices all are…

Effects of cannabis legalisation on patterns of cannabis consumption among adolescents in Ontario, Canada (2001- 2019)

Created by Sameer Imtiaz, Yeshambel Nigatu, Marcos Sanches, Farihah Ali, Angela Boak, Laura Douglas, Hayley Hamilton, Jürgen Rehm, Sergio Rueda, Robert Schwartz, Samantha Wells, Tara Elton-Marshall.

Cannabis legalisation was enacted on 17 October 2018 in Canada. Accordingly, the effects of cannabis legalisation on patterns of cannabis consumption were examined among adolescents…

Cannabis Legalization and Driving under the Influence of Cannabis and Driving under the Influence of Alcohol among Adult and Adolescent Drivers in Ontario, Canada (2001–2019).

Created by Sameer Imtiaz, Yeshambel Nigatu, Farihah Ali, Branka Agic, Tara Elton-Marshall, Huan Jiang, Jürgen Rehm, Sergio Rueda…

Background The impacts of cannabis legalization on driving under the influence of cannabis and driving under the influence of alcohol among adults and adolescents were examined in Ontario, Canada…

How Does Alcohol Use Impact Morbidity and Mortlity of Liver Cirrhosis? A Systematic Review and Dose–Response Meta-Analysis.

Created by Laura Llamosas-Falcón, Charlotte Probst, Charlotte Buckley, Huan Jiang, Aurélie Lasserre, Klajdi Puka, Alexander Tran, Yachen Zhu & Jürgen Rehm.

Alcohol consumption is the most important risk factor responsible for the disease burden of liver cirrhosis (LC). Estimates of risk relationships available usually neither…

A public health perspective on mitigating the global burden of chronic liver disease

Maya Balakrishnan, Jürgen Rehm

Chronic liver disease is a significant global health problem. Epidemiological trends do not show improvement in chronic liver disease incidence but rather a shift in etiologies, with steatotic liver disease (SLD) from metabolic dysfunction and alcohol becoming increasingly important causes…

Trends and projection in the proportion of (heavy) cannabis use in Germany from 1995 to 2021

Created by Sally Olderbak, Justin Mockl, Jakob Manthey, Sara Lee, Jürgen Rehm, Eva Hoch, Ludwig Kraus.

To measure the current trends of cannabis use in Germany, measure trends in the proportion of heavy cannabis users and estimate future cannabis use rates…

Youth Cannabis Use and Subsequent Health Service Use for Mood and Anxiety Disorders: A Population-Based Cohort Study.

Created by André McDonald, Paul Kurdyak, Jürgen Rehm, Michael Roerecke & Susan Bondy.

Epidemiologic research suggests a modest association between youth cannabis use and mood and anxiety disorders (MADs). However, current evidence is based mostly on cohort studies using data from the 20th century when cannabis was significantly less potent than today…