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J. & Manthey, J. 2021. Guidelines and reality in studies on the economic costs of alcohol use: a systematic review. The International Journal of Alcohol and Drug Research.

Carvalho, A.F., Maes, M., Solmi, M., Brunoni, A.R., Lange, S., Husain, M.I., Kurdyak, P., Rehm, J. & Koyanagi, A. 2021. Is dynapenia associated with the onset and persistence of depressive and anxiety symptoms among older adults? Findings from the Irish longitudinal study on ageing. Aging Ment Health, 25(3):468-475.

Chavarria, J., Wells, S., Elton-Marshall, T. & Rehm, J. 2021. Associations of antidepressant use with alcohol use and problem drinking: Ontario population data from 1999 to 2017. Can J Public Health.

Chrystoja, B.R., Monteiro, M.G., Owe, G., Gawryszewski, V.

M., Ferreira-Borges, C., Bryun, E., Fadeeva, E., Gil, A., Koshkina, E., Nadezhdin, A., Tetenova, E., Vyshinsky, K., Yurasova, E. & Rehm, J. 2021. The Russian translations of the Alcohol Use Disorders Identification Test (AUDIT): A document analysis and discussion of implementation challenges. International Journal of Alcohol and Drug Research, 9(1):20-29.

Carr, S., Rehm, J. & Manthey, J. 2021. Guidelines and reality in studies on the economic costs of alcohol use: a systematic review. The International Journal of Alcohol and Drug Research.

Carvalho, A.F., Maes, M., Solmi, M., Brunoni, A.R., Lange, S., Husain, M.I., Kurdyak, P., Rehm, J. &

Shield

Koyanagi,

K

A. 2021.

Mortality in the Americas from 2013 to 2015 resulting from diseases, conditions and injuries Psychopharmacology (Berl)

Is dynapenia associated with the onset and persistence of depressive and anxiety symptoms among older adults? Findings from the Irish longitudinal study on ageing. Aging Ment Health, 25(3):468-475.

Chavarria, J., Wells, S., Elton-Marshall, T. & Rehm, J. 2021. Associations of antidepressant use with alcohol use and problem drinking: Ontario population data from 1999 to 2017. Can J Public Health.

Chrystoja, B.R., Monteiro, M.G., Owe, G., Gawryszewski, V.P., Rehm, J. & Shield, K. 2021. Mortality in the Americas from 2013 to 2015 resulting from diseases, conditions and injuries which are 100% alcohol-attributable. Addiction.

Chrystoja, B.R., Rehm, J., Manthey, J., Probst, C., Wettlaufer, A. & Shield, K.D. 2021. A systematic comparison of the global comparative risk assessments for alcohol. Addiction.

Crépault, J.-F., Rehm, J. & Room, R. 2021. Legalization as more effective control? Parallels between the end of alcohol prohibition (1927) and the legalization of cannabis (2018) in Ontario, Canada. International Journal of Drug Policy, 97:103367.

Crepault, J.F., Watson, T.M., Strike, C., Bonato, S. & Rehm, J. 2021. What is a public health approach to substance use? Protocol for a qualitative systematic review. BMJ Open, 11(10):e055991.

Elton-Marshall, T., Ali, F., Narkar, R., Hyshka, E., Shahin, R., Hopkins, S., Imtiaz, S., Graham, B., Garber, G. & Rehm, J. 2021. Harm reduction worker safety during the COVID-19 global

Elton-Marshall, T., Wells, S., Jankowicz, D., Nigatu, Y.T., Wickens, C.M., Rehm, J. & Hamilton, H.A. 2021. Multiple COVID-19 Risk Factors Increase the Likelihood of Experiencing Anxiety Symptoms in Canada. Can J Psychiatry, 66(1):56-58.

Fares, A., Wickens, C.M., Mann, R.E., Di Ciano, P., Wright, M., Matheson, J., Hasan, O.S.M., Rehm, J., George, T.P., Samokhvalov, A.V., Shuper, P.A., Huestis, M.A., Stoduto, G., Brown, T., Stefan, C., Rubin-Kahana, D.S., Le Foll, B. & Brands, B. 2021.

Combined effect of alcohol and cannabis on simulated driving.

Combined effect of alcohol and cannabis on simulated driving. Psychopharmacology (Berl).

Frischknecht, U., Hoffmann, S., Steinhauser, A., Lindemann, C., Buchholz, A., Manthey, J., Schulte, B., Rehm, J., Kraus, L., Verthein, U., Reimer, J. & Kiefer, F. 2021. Diagnosis and treatment of alcohol-Related disorders – a survey of health care providers to develop strategies for the implementation of guidelines. Suchttherapie, 22(03):141-151.

Haleem, A., Hwang, Y.J., Elton-Marshall, T., Rehm, J. & Imtiaz, S. 2021. The longitudinal relationship between cannabis use and hypertension. Drug Alcohol Rev.

Heilig, M., MacKillop, J., Martinez, D., Rehm, J., Leggio, L. & Vanderschuren, L. 2021. Addiction as a brain disease revised: why it still matters, and the need for consilience. Neuropsychopharmacology.

Heilig, M., MacKillop, J., Martinez, D., Rehm, J., Leggio, L. & Vanderschuren, L.J.M.J. 2021. Response to “Addiction is a social disease: just as tenable as calling it a brain disease”. Neuropsychopharmacology.

Imtiaz, S., Elton-Marshall, T. & Rehm, J. 2021. Cannabis liberalisation and the US opioid crisis. BMJ, 372:n163.

Imtiaz, S., Nafeh, F., Russell, C., Ali, F., Elton-Marshall, T. & Rehm, J. 2021. The impact of the novel coronavirus disease (COVID-19) pandemic on drug overdose-related deaths in the United States and Canada: a systematic review of observational studies and analysis of public health surveillance data. Subst Abuse Treat Prev Policy, 16(1):87.

Imtiaz, S., Wells, S., Rehm, J., Hamilton, H.A., Nigatu, Y.T., Wickens, C.M., Jankowicz, D. & Elton-Marshall, T. 2021. Cannabis Use During the COVID-19 Pandemic in Canada: A Repeated Cross-sectional Study. Journal of addiction medicine, 15(6):484-490.

Jane-Llopis, E., Anderson, P., Segura, L., Zabaleta, E., Munoz, R., Ruiz, G., Rehm, J., Cabezas, C. & Colom, J. 2021. Mental ill-health during COVID-19 confinement. BMC Psychiatry, 21(1):194.

Jiang, H., Lange, S., Tran, A., Imtiaz, S. & Rehm, J. 2021. Determining the sex-specific distributions of average daily alcohol consumption using cluster analysis: is there a separate distribution for people with alcohol dependence? Popul Health Metr, 19(1):28.

Kilian, C., Manthey, J., Carr, S., Hanschmidt, F., Rehm, J., Speerforck, S. & Schomerus, G. 2021. Stigmatization of people with alcohol use disorders: An updated systematic review of population studies. Alcohol Clin Exp Res, 45(5):899-911.

Kilian, C., Manthey, J., Kraus, L., Makela, P., Moskalewicz, J., Sieroslawski, J. & Rehm, J. 2021. A new perspective on European drinking cultures: A model-based approach to determine variations in drinking practices across 19 European countries. Addiction.

Kilian, C., Rehm, J., Allebeck, P., Bartak, M., Braddick, F., Gual, A., Matrai, S., Petruzelka, B., Rogalewicz, V., Rossow, I., Schulte, B., Stelemekas, M. & Manthey, J. 2021. Conducting a multi-country online alcohol survey in the time of the COVID-19 pandemic: Opportunities and challenges. Int J Methods Psychiatr Res.

Kilian, C., Rehm, J., Allebeck, P., Braddick, F., Gual, A., Bartak, M., Bloomfield, K., Gil, A., Neufeld, M., O'Donnell, A., Petruzelka, B., Rogalewicz, V., Schulte, B., Manthey, J., European Study Group on Alcohol, U. & Covid 2021. Alcohol consumption during the COVID-19 pandemic in Europe: a large-scale cross-sectional study in 21 countries. Addiction.

Kilian, C., Rovira, P., Neufeld, M., Ferreira-Borges, C., Rumgay, H., Soerjomataram, I. & Rehm, J. 2021. Modelling the impact of increased alcohol taxation on alcohol-attributable cancers in the WHO European Region. Lancet Reg Health Eur, 11:100225.

Kokole, D., Mercken, L., Jane-Llopis, E., Natera Rey, G., Arroyo, M., Medina, P., Perez-Gomez, A., Mejia-Trujillo, J., Piazza, M., Bustamante, I.V., O'Donnell, A., Kaner, E., Gual, A., Lopez-Pelayo, H., Schulte, B., Manthey, J., Rehm, J., Anderson, P. & de Vries, H. 2021. Perceived appropriateness of alcohol screening and brief advice programmes in Colombia, Mexico and Peru and barriers to their implementation in primary health care - a cross-sectional survey. Prim Health Care Res Dev, 22:e4.

Lachenmeier, D.W., Neufeld, M. & Rehm, J. 2021. The Impact of Unrecorded Alcohol Use on Health: What Do We Know in 2020? J Stud Alcohol Drugs, 82(1):28-41.

Lange, S., Bagge, C., Probst, C. & Rehm, J. 2021. Proportion of Individuals With Past-Year Suicidal Ideation Who Attempted Suicide Over the Past 10 Years in the United States, and the Influence of Age and Sex. Crisis, 42(2):152-156.

Lange, S. & Rehm, J. 2021. Commentary: The COVID-19 Pandemic Is Not a Good Time to Weaken Restrictions on Alcohol Availability. Healthc Policy, 16(4):25-30.

Llamosas-Falcon, L., Shield, K.D., Gelovany, M., Hasan, O.S.M., Manthey, J., Monteiro, M., Walsh, N. & Rehm, J. 2021. Impact of alcohol on the progression of HCV-related liver disease: A systematic review and meta-analysis. J Hepatol.

Lopez-Pelayo, H., Campeny, E., Oliveras, C., Rehm, J., Manthey, J., Gual, A. & Balcells-Olivero, M.L.M. 2021. Early, chronic, and acute cannabis exposure and their relationship with cognitive and behavioral harms. Front Psychiatry, 12:643556.

Lopez-Pelayo, H., Matrai, S., Balcells-Olivero, M., Campeny, E., Braddick, F., Bossong, M.G., Cruz, O.S., Deluca, P., Dom, G., Feingold, D., Freeman, T.P., Guzman, P., Hindocha, C., Kelly, B.C., Liebregts, N., Lorenzetti, V., Manthey, J., Matias, J., Oliveras, C., Pons, M.T., Rehm, J., Rosenkranz, M., Swithenbank, Z., van Deurse, L., Vicente, J., Vuolo, M., Wojnar, M. & Gual, A. 2021. Standard units for cannabis dose: Why is it important to standardize cannabis dose for drug policy and how can we enhance its place on the public health agenda? Int J Drug Policy, 97:103350.

Lopez-Pelayo, H., Matrai, S., Balcells-Olivero, M., Campeny, E., Braddick, F., Bossong, M.G., Cruz, O.S., Deluca, P., Dom, G., Feingold, D., Freeman, T.P., Guzman, P., Hindocha, C., Kelly, B.C., Liebregts, N., Lorenzetti, V., Manthey, J., Matias, J., Oliveras, C., Pons, M.T., Rehm, J., Rosenkranz, M., Swithenbank, Z., van Deurse, L., Vicente, J., Vuolo, M., Wojnar, M. & Gual, A. 2021. Supporting future cannabis policy - Developing a standard joint unit: A brief back-casting exercise. Front Psychiatry, 12:675033.

Manthey, J., Freeman, T.P., Kilian, C., Lopez-Pelayo, H. & Rehm, J. 2021. Public health monitoring of cannabis use in Europe: prevalence of use, cannabis potency, and treatment rates. Lancet Reg Health Eur, 10:100227.

Manthey, J., Hassan, S.A., Carr, S., Kilian, C., Kuitunen-Paul, S. & Rehm, J. 2021. Estimating the economic consequences of substance use and substance use disorders. Expert Rev Pharmacoecon Outcomes Res:1-8.

Manthey, J., Hassan, S.A., Carr, S., Kilian, C., Kuitunen-Paul, S. & Rehm, J. 2021. What are the Economic Costs to Society Attributable to Alcohol Use? A Systematic Review and Modelling Study. Pharmacoeconomics, 39(7):809-822.

Manthey, J., Kilian, C., Carr, S., Bartak, M., Bloomfield, K., Braddick, F., Gual, A., Neufeld, M., O'Donnell, A., Petruzelka, B., Rogalewicz, V., Rossow, I., Schulte, B. & Rehm, J. 2021. Use of alcohol, tobacco, cannabis, and other substances during the first wave of the SARS-CoV-2 pandemic in Europe: a survey on 36,000 European substance users. Subst Abuse Treat Prev Policy, 16(1):36.

Manthey, J., Solovei, A., Anderson, P., Carr, S. & Rehm, J. 2021. Can alcohol consumption in Germany be reduced by alcohol screening, brief intervention and referral to treatment in primary health care? Results of a simulation study. PLOS ONE, 16(8):e0255843.

McDonald, A.J., Cook, S., Turner, N.E., Ialomiteanu, A.R., Mann, R.E., Bondy, S.J., Roerecke, M., McCready, J., Millstone, D., Hamilton, H.A., Elton-Marshall, T., Rehm, J., Kurdyak, P., Ilie, G., Vingilis, E.R., Wickens, C.M., van der Maas, M. & Cusimano, M.D. 2021. Adult attention-deficit hyperactivity disorder symptoms and psychological distress, hazardous drinking, and problem gambling: A population-based study. Psychiatry Res, 301:113985.

Minian, N., Noormohamed, A., Lingam, M., Zawertailo, L., Le Foll, B., Rehm, J., Giesbrecht, N., Samokhvalov, A.V., Baliunas, D. & Selby, P. 2021. Integrating a brief alcohol intervention with tobacco addiction treatment in primary care: qualitative study of health care practitioner perceptions. Addict Sci Clin Pract, 16(1):17.

Monteiro, M.G., Martins, C.B., Sanchez, Z.M., Rehm, J., Shield, K., Falade, R., MacDiarmid, J. & Trangenstein, P. 2021. Assessing Sustainable Development Goal Target Indicator 3.5.2: Trends in alcohol per capita consumption in the Americas 1990-2016. Rev Panam Salud Publica, 45:e142.

Morojele, N.K., Shenoi, S.V., Shuper, P.A., Braithwaite, R.S. & Rehm, J. 2021. Alcohol Use and the Risk of Communicable Diseases. Nutrients, 13(10).

Neufeld, M., Bobrova, A., Davletov, K., Stelemekas, M., Stoppel, R., Ferreira-Borges, C., Breda, J. & Rehm, J. 2021. Alcohol control policies in Former Soviet Union countries: A narrative review of three decades of policy changes and their apparent effects. Drug Alcohol Rev, 40(3):350-367.

Neufeld, M., Bunova, A., Ferreira-Borges, C., Bryun, E., Fadeeva, E., Gil, A., Gornyi, B., Khaltourina, D., Koshkina, E., Nadezhdin, A., Tetenova, E., Vujnovic, M., Vyshinsky, K., Yurasova, E. & Rehm, J. 2021. The Alcohol Use Disorders Identification Test (AUDIT) in the Russian language - a systematic review of validation efforts and application challenges. Subst Abuse Treat Prev Policy, 16(1):76.

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, J., Bunova, A., Gil, A., Gornyi, B., Rovira, P., Manthey, J., Yurasova, E., Dolgova, S., Idrisov, B., Moskvicheva, M., Nabiullina, G., Shegaym, O., Zhidkova, I., Ziganshina, Z., Ferreira-Borges, C., the, R.U.S.A.C. & the, R.U.S.A.P.A.B. 2021. Validation of a screening test for alcohol use, the Russian Federation. Bull World Health Organ, 99(7):496-505.

O'Donnell, A., Schulte, B., Manthey, J., Schmidt, C.S., Piazza, M., Chavez, I.B., Natera, G., Aguilar, N.B., Hernandez, G.Y.S., Mejia-Trujillo, J., Perez-Gomez, A., Gual, A., de Vries, H., Solovei, A., Kokole, D., Kaner, E., Kilian, C., Rehm, J., Anderson, P. & Jane-Llopis, E. 2021. Primary care-based screening and management of depression amongst heavy drinking patients: Interim secondary outcomes of a three-country quasi-experimental study in Latin America. PLoS One, 16(8):e0255594.

Patra, J., Buckley, C., Kerr, W.C., Brennan, A., Purshouse, R.C. & Rehm, J. 2021. Impact of body mass and alcohol consumption on all-cause and liver mortality in 240 000 adults in the United States. Drug Alcohol Rev.

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, J., Bunova, A., Gil, A., Gornyi, B., Rovira, P., Manthey, J., Yurasova, E., Dolgova, S., Idrisov, B., Moskvicheva, M., Nabiullina, G., Shegaym, O., Zhidkova, I., Ziganshina, Z., Ferreira-Borges, C., The RUS Audit Collaborators & The RUS Audit Project Advisory Board 2021. Validation of a screening test for alcohol use, the Russian Federation. Bull World Health Organ, 99(7):496-505.

O'Donnell, A., Schulte, B., Manthey, J., Schmidt, C.S., Piazza, M., Chavez, I.B., Natera, G., Aguilar, N.B., Hernandez, G.Y.S., Mejia-Trujillo, J., Perez-Gomez, A., Gual, A., de Vries, H., Solovei, A., Kokole, D., Kaner, E., Kilian, C., Rehm, J., Anderson, P. & Jane-Llopis, E. 2021. Primary care-based screening and management of depression amongst heavy drinking patients: Interim secondary outcomes of a three-country quasi-experimental study in Latin America. PLoS One, 16(8):e0255594.

Patra, J., Buckley, C., Kerr, W.C., Brennan, A., Purshouse, R.C. & Rehm, J. 2021. Impact of body mass and alcohol consumption on all-cause and liver mortality in 240 000 adults in the United States. Drug Alcohol Rev.

Popova, S., Dozet, D., O'Hanlon, G., Temple, V., Rehm, J. 2021. Maternal alcohol use, adverse neonatal outcomes and pregnancy complications in British Columbia, Canada: a population-based study. BMC Pregnancy Childbirth, 21(1):74.

Popova, S., Dozet, D., Shield, K., Rehm, J. & Burd, L. 2021. Alcohol's Impact on the Fetus. Nutrients, 13(10).

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Health, social and legal outcomes of individuals with diagnosed or at risk for fetal alcohol spectrum disorder: Canadian example. Drug Alcohol Depend, 219:108487.

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Probst, C., Lange, S., Kilian, C., Saul, C. & Rehm, J. 2021.

Health, social and legal outcomes of individuals with diagnosed or at risk for fetal alcohol spectrum disorder: Canadian example. Drug Alcohol Depend, 219:108487

The dose-response relationship between socioeconomic deprivation and alcohol-attributable mortality risk-a systematic review and meta-analysis. BMC Med, 19(1):268.

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Rumgay, H., Shield, K., Charvat, H., Ferrari, P., Sornpaisarn, B., Obot, I., Islami, F., Lemmens, V., Rehm, J. & Soerjomataram, I. 2021. Global burden of cancer in 2020 attributable to alcohol consumption: a population-based study. Lancet Oncol, 22(8):1071-1080.

Russell, C., Ali, F., Nafeh, F., LeBlanc, S., Imtiaz, S., Elton-Marshall, T. & Rehm, J. 2021. A qualitative examination of substance use service needs among people who use drugs (PWUD) with treatment and service experience in Ontario, Canada. BMC Public Health, 21(1):2021.