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Rehm, J., Babor, T.F., Casswell, S. & Room, R. 2021. Heterogeneity in trends of alcohol use around the world: Do policies make a difference? Drug Alcohol Rev, 40(3):345-349.

Rehm, J., Kilian, C. & Manthey, J. 2021. Future of surveys in the alcohol field. Drug Alcohol Rev, 40(2):176-178.

Rehm, J., Kilian, C., Rovira, P., Shield, K.D. & Manthey, J. 2021. The elusiveness of representativeness in general population surveys for alcohol. Drug Alcohol Rev, 40(2):161-165.

Rehm, J., Patra, J., Brennan, A., Buckley, C., Greenfield, T.K., Kerr, W.C., Manthey, J., Purshouse, R.C., Rovira, P., Shuper, P.A. & Shield, K.D. 2021. The role of alcohol use in the aetiology and progression of liver disease: A narrative review and a quantification. Drug Alcohol Rev.

Rehm, J., Probst, C., Falcón, L.L. & Shield, K.D. 2021. Burden of Disease: The Epidemiological Aspects of Addiction. In: El-Guebaly, Nady, Carrà, Giuseppe, Galanter, Marc & Baldacchino, Alexander M. (eds.). Textbook of Addiction Treatment: International Perspectives. 51-64. Cham: Springer International Publishing.

Rehm, J. & Purshouse, R.C. 2021. Causality and initiation of alcohol control policy. A response to Allamani. Drug and Alcohol Review.

Rehm, J., Rovira, P., Llamosas-Falcón, L. & Shield, K.D. 2021. Dose–response relationships between levels of alcohol use and risks of mortality or disease, for all people, by age, sex, and specific risk factors. Nutrients, 13(8):2652.

Rehm, J. & Shield, K.D. 2021. Alcohol Use and Cancer in the European Union. Eur Addict Res, 27(1):1-8.

Rehm, J., Stelemekas, M., Ferreira-Borges, C., Jiang, H., Lange, S., Neufeld, M., Room, R., Casswell, S., Tran, A. & Manthey, J. 2021. Classifying Alcohol Control Policies with Respect to Expected Changes in Consumption and Alcohol-Attributable Harm: The Example of Lithuania, 2000-2019. Int J Environ Res Public Health, 18(5).

Ali, F., Russell, C., Nafeh, F., Rehm, J., LeBlanc, S. & Elton-Marshall, T. 2021. Changes in substance supply and use characteristics among people who use drugs (PWUD) during the COVID-19 global pandemic: A national qualitative assessment in Canada. International Journal of Drug Policy:103237.

Anderson, P., Manthey, J., Llopis, E.J., Rey, G.N., Bustamante, I.V., Piazza, M., Aguilar, P.S.M., Mejia-Trujillo, J., Perez-Gomez, A., Rowlands, G., Lopez-Pelayo, H., Mercken, L., Kokole, D., O'Donnell, A., Solovei, A., Kaner, E., Schulte, B., de Vries, H., Schmidt, C., Gual, A. & Rehm, J. 2021. Impact of Training and Municipal Support on Primary Health Care-Based Measurement of Alcohol Consumption in Three Latin American Countries: 5-Month Outcome Results of the Quasi-experimental Randomized SCALA Trial. J Gen Intern Med.

Anderson, P., O'Donnell, A., Kaner, E., Llopis, E.J., Manthey, J. & Rehm, J. 2021. Impact of minimum unit pricing on alcohol purchases in Scotland and Wales: controlled interrupted time series analyses. Lancet Public Health.

Babor, T.F., Casswell, S., Rehm, J., Room, R. & Rossow, I. 2021. A Festival of Epiphanies: Three Revelations in Support of Better Alcohol Control Policies. Journal of Studies on Alcohol and Drugs, 82(1):5-8.

Barrio, P., Baldaqui, N., Andreu, M., Kilian, C., Rehm, J., Gual, A. & Manthey, J. 2021. Abstinence among alcohol use disorder patients during the COVID-19 pandemic: Insights from spain. Alcohol Clin Exp Res.

Brennan, A., Buckley, C., Vu, T.M., Probst, C., Nielsen, A., Bai, H., Broomhead, T., Greenfield, T., Kerr, W., Meier, P.S., Rehm, J., Shuper, P., Strong, M. & Purshouse, R.C. 2020. Introducing CASCADEPOP: an open-source sociodemographic simulation platform for US health policy appraisal. Int J Microsimul, 13(2):21-60.

Bruguera, P., Barrio, P., Manthey, J., Oliveras, C., Lopez-Pelayo, H., Nuno, L., Miquel, L., Lopez-Lazcano, A., Blithikioti, C., Caballeria, E., Matrai, S., Rehm, J., Vieta, E. & Gual, A. 2021. Mid and long-term effects of a SBIRT program for at-risk drinkers attending to an emergency department. Follow-up results from a randomized controlled trial. Eur J Emerg Med.

Carr, S., Rehm, J. & Manthey, J. 2021. Guidelines and reality in studies on the economic costs of alcohol use: a systematic review. The International Journal of Alcohol and Drug Research.

Carvalho, A.F., Maes, M., Solmi, M., Brunoni, A.R., Lange, S., Husain, M.I., Kurdyak, P., Rehm, J. & Koyanagi, A. 2021. Is dynapenia associated with the onset and persistence of depressive and anxiety symptoms among older adults? Findings from the Irish longitudinal study on ageing. Aging Ment Health, 25(3):468-475.

Chavarria, J., Wells, S., Elton-Marshall, T. & Rehm, J. 2021. Associations of antidepressant use with alcohol use and problem drinking: Ontario population data from 1999 to 2017. Can J Public Health.

Chrystoja, B.R., Monteiro, M.G., Owe, G., Gawryszewski, V.P., Rehm, J. & Shield, K. 2021. Mortality in the Americas from 2013 to 2015 resulting from diseases, conditions and injuries which are 100% alcohol-attributable. Addiction.

Chrystoja, B.R., Rehm, J., Manthey, J., Probst, C., Wettlaufer, A. & Shield, K.D. 2021. A systematic comparison of the global comparative risk assessments for alcohol. Addiction.

Crépault, J.-F., Rehm, J. & Room, R. 2021. Legalization as more effective control? Parallels between the end of alcohol prohibition (1927) and the legalization of cannabis (2018) in Ontario, Canada. International Journal of Drug Policy, 97:103367.

Crepault, J.F., Watson, T.M., Strike, C., Bonato, S. & Rehm, J. 2021. What is a public health approach to substance use? Protocol for a qualitative systematic review. BMJ Open, 11(10):e055991.

Elton-Marshall, T., Ali, F., Narkar, R., Hyshka, E., Shahin, R., Hopkins, S., Imtiaz, S., Graham, B., Garber, G. & Rehm, J. 2021. Harm reduction worker safety during the COVID-19 global

Elton-Marshall, T., Wells, S., Jankowicz, D., Nigatu, Y.T., Wickens, C.M., Rehm, J. & Hamilton, H.A. 2021. Multiple COVID-19 Risk Factors Increase the Likelihood of Experiencing Anxiety Symptoms in Canada. Can J Psychiatry, 66(1):56-58.

Fares, A., Wickens, C.M., Mann, R.E., Di Ciano, P., Wright, M., Matheson, J., Hasan, O.S.M., Rehm, J., George, T.P., Samokhvalov, A.V., Shuper, P.A., Huestis, M.A., Stoduto, G., Brown, T., Stefan, C., Rubin-Kahana, D.S., Le Foll, B. & Brands, B. 2021. Combined effect of alcohol and cannabis on simulated driving. Psychopharmacology (Berl).

Haleem, A., Hwang, Y.J., Elton-Marshall, T., Rehm, J. & Imtiaz, S. 2021. The longitudinal relationship between cannabis use and hypertension. Drug Alcohol Rev.

Heilig, M., MacKillop, J., Martinez, D., Rehm, J., Leggio, L. & Vanderschuren, L. 2021. Addiction as a brain disease revised: why it still matters, and the need for consilience. Neuropsychopharmacology.

Heilig, M., MacKillop, J., Martinez, D., Rehm, J., Leggio, L. & Vanderschuren, L.J.M.J. 2021. Response to “Addiction is a social disease: just as tenable as calling it a brain disease”. Neuropsychopharmacology.

Imtiaz, S., Elton-Marshall, T. & Rehm, J. 2021. Cannabis liberalisation and the US opioid crisis. BMJ, 372:n163.

Jane-Llopis, E., Anderson, P., Segura, L., Zabaleta, E., Munoz, R., Ruiz, G., Rehm, J., Cabezas, C. & Colom, J. 2021. Mental ill-health during COVID-19 confinement. BMC Psychiatry, 21(1):194.

Jiang, H., Lange, S., Tran, A., Imtiaz, S. & Rehm, J. 2021. Determining the sex-specific distributions of average daily alcohol consumption using cluster analysis: is there a separate distribution for people with alcohol dependence? Popul Health Metr, 19(1):28.

Kilian, C., Manthey, J., Carr, S., Hanschmidt, F., Rehm, J., Speerforck, S. & Schomerus, G. 2021. Stigmatization of people with alcohol use disorders: An updated systematic review of population studies. Alcohol Clin Exp Res, 45(5):899-911.

Kilian, C., Manthey, J., Kraus, L., Makela, P., Moskalewicz, J., Sieroslawski, J. & Rehm, J. 2021. A new perspective on European drinking cultures: A model-based approach to determine variations in drinking practices across 19 European countries. Addiction.

Kilian, C., Rehm, J., Allebeck, P., Bartak, M., Braddick, F., Gual, A., Matrai, S., Petruzelka, B., Rogalewicz, V., Rossow, I., Schulte, B., Stelemekas, M. & Manthey, J. 2021. Conducting a multi-country online alcohol survey in the time of the COVID-19 pandemic: Opportunities and challenges. Int J Methods Psychiatr Res.

Kilian, C., Rehm, J., Allebeck, P., Braddick, F., Gual, A., Bartak, M., Bloomfield, K., Gil, A., Neufeld, M., O'Donnell, A., Petruzelka, B., Rogalewicz, V., Schulte, B., Manthey, J., European Study Group on Alcohol, U. & Covid 2021. Alcohol consumption during the COVID-19 pandemic in Europe: a large-scale cross-sectional study in 21 countries. Addiction.

Kokole, D., Mercken, L., Jane-Llopis, E., Natera Rey, G., Arroyo, M., Medina, P., Perez-Gomez, A., Mejia-Trujillo, J., Piazza, M., Bustamante, I.V., O'Donnell, A., Kaner, E., Gual, A., Lopez-Pelayo, H., Schulte, B., Manthey, J., Rehm, J., Anderson, P. & de Vries, H. 2021. Perceived appropriateness of alcohol screening and brief advice programmes in Colombia, Mexico and Peru and barriers to their implementation in primary health care - a cross-sectional survey. Prim Health Care Res Dev, 22:e4.

Lachenmeier, D.W., Neufeld, M. & Rehm, J. 2021. The Impact of Unrecorded Alcohol Use on Health: What Do We Know in 2020? J Stud Alcohol Drugs, 82(1):28-41.

Lange, S., Bagge, C., Probst, C. & Rehm, J. 2021. Proportion of Individuals With Past-Year Suicidal Ideation Who Attempted Suicide Over the Past 10 Years in the United States, and the Influence of Age and Sex. Crisis, 42(2):152-156.

Lange, S. & Rehm, J. 2021. Commentary: The COVID-19 Pandemic Is Not a Good Time to Weaken Restrictions on Alcohol Availability. Healthc Policy, 16(4):25-30.

Llamosas-Falcon, L., Shield, K.D., Gelovany, M., Hasan, O.S.M., Manthey, J., Monteiro, M., Walsh, N. & Rehm, J. 2021. Impact of alcohol on the progression of HCV-related liver disease: A systematic review and meta-analysis. J Hepatol.

Lopez-Pelayo, H., Campeny, E., Oliveras, C., Rehm, J., Manthey, J., Gual, A. & Balcells-Olivero, M.L.M. 2021. Early, chronic, and acute cannabis exposure and their relationship with cognitive and behavioral harms. Front Psychiatry, 12:643556.

Lopez-Pelayo, H., Matrai, S., Balcells-Olivero, M., Campeny, E., Braddick, F., Bossong, M.G., Cruz, O.S., Deluca, P., Dom, G., Feingold, D., Freeman, T.P., Guzman, P., Hindocha, C., Kelly, B.C., Liebregts, N., Lorenzetti, V., Manthey, J., Matias, J., Oliveras, C., Pons, M.T., Rehm, J., Rosenkranz, M., Swithenbank, Z., van Deurse, L., Vicente, J., Vuolo, M., Wojnar, M. & Gual, A. 2021. Standard units for cannabis dose: Why is it important to standardize cannabis dose for drug policy and how can we enhance its place on the public health agenda? Int J Drug Policy, 97:103350.

Lopez-Pelayo, H., Matrai, S., Balcells-Olivero, M., Campeny, E., Braddick, F., Bossong, M.G., Cruz, O.S., Deluca, P., Dom, G., Feingold, D., Freeman, T.P., Guzman, P., Hindocha, C., Kelly, B.C., Liebregts, N., Lorenzetti, V., Manthey, J., Matias, J., Oliveras, C., Pons, M.T., Rehm, J., Rosenkranz, M., Swithenbank, Z., van Deurse, L., Vicente, J., Vuolo, M., Wojnar, M. & Gual, A. 2021. Supporting future cannabis policy - Developing a standard joint unit: A brief back-casting exercise. Front Psychiatry, 12:675033.McDonald

Manthey, A. J., CookHassan, S., Turner, N.E., Ialomiteanu, A.R., Mann, R.E., Bondy, S.J., Roerecke, M., McCready, J., Millstone, D., Hamilton, H.A., Elton-Marshall, T., Rehm, J., Kurdyak, P., Ilie, G., Vingilis, E.R., Wickens, C.M., van der Maas, M. & Cusimano, M.D. 2021. Adult attention-deficit hyperactivity disorder symptoms and psychological distress, hazardous drinking, and problem gambling: A population-based study. Psychiatry Res, 301:113985.Manthey, J., Hassan, S.A., Carr, S., Kilian, C., Kuitunen-Paul, SA., Carr, S., Kilian, C., Kuitunen-Paul, S. & Rehm, J. 2021. Estimating the economic consequences of substance use and substance use disorders. Expert Rev Pharmacoecon Outcomes Res:1-8.

Manthey, J., Hassan, S.A., Carr, S., Kilian, C., Kuitunen-Paul, S. & Rehm, J. 2021. What are the Economic Costs to Society Attributable to Alcohol Use? A Systematic Review and Modelling Study. Pharmacoeconomics, 39(7):809-822.

Manthey, J., Kilian, C., Carr, S., Bartak, M., Bloomfield, K., Braddick, F., Gual, A., Neufeld, M., O'Donnell, A., Petruzelka, B., Rogalewicz, V., Rossow, I., Schulte, B. & Rehm, J. 2021. Estimating the economic consequences of substance use and substance use disorders. Expert Rev Pharmacoecon Outcomes Res:1-8.

Manthey, J., Hassan, S.A., Carr, S., Kilian, C., Kuitunen-Paul, S. & Rehm, J. 2021. What are the Economic Costs to Society Attributable to Alcohol Use? A Systematic Review and Modelling Study. Pharmacoeconomics, 39(7):809-822.

Manthey, J., Kilian, C., Carr, S., Bartak, M., Bloomfield, K., Braddick, F., Gual, A., Neufeld, M., O'Donnell, A., Petruzelka, B., Rogalewicz, V., Rossow, I., Schulte, B. & Rehm, J. 2021. Use of alcohol, tobacco, cannabis, and other substances during the first wave of the SARS-CoV-2 pandemic in Europe: a survey on 36,000 European substance users. Subst Abuse Treat Prev Policy, 16(1):36Use of alcohol, tobacco, cannabis, and other substances during the first wave of the SARS-CoV-2 pandemic in Europe: a survey on 36,000 European substance users. Subst Abuse Treat Prev Policy, 16(1):36.

McDonald, A.J., Cook, S., Turner, N.E., Ialomiteanu, A.R., Mann, R.E., Bondy, S.J., Roerecke, M., McCready, J., Millstone, D., Hamilton, H.A., Elton-Marshall, T., Rehm, J., Kurdyak, P., Ilie, G., Vingilis, E.R., Wickens, C.M., van der Maas, M. & Cusimano, M.D. 2021. Adult attention-deficit hyperactivity disorder symptoms and psychological distress, hazardous drinking, and problem gambling: A population-based study. Psychiatry Res, 301:113985.

Minian, N., Noormohamed, A., Lingam, M., Zawertailo, L., Le Foll, B., Rehm, J., Giesbrecht, N., Samokhvalov, A.V., Baliunas, D. & Selby, P. 2021. Integrating a brief alcohol intervention with tobacco addiction treatment in primary care: qualitative study of health care practitioner perceptions. Addict Sci Clin Pract, 16(1):17.

Neufeld, M., Bobrova, A., Davletov, K., Stelemekas, M., Stoppel, R., Ferreira-Borges, C., Breda, J. & Rehm, J. 2021. Alcohol control policies in Former Soviet Union countries: A narrative review of three decades of policy changes and their apparent effects. Drug Alcohol Rev, 40(3):350-367.

Neufeld, M., Bunova, A., Ferreira-Borges, C., Bryun, E., Fadeeva, E., Gil, A., Gornyi, B., Khaltourina, D., Koshkina, E., Nadezhdin, A., Tetenova, E., Vujnovic, M., Vyshinsky, K., Yurasova, E. & Rehm, J. 2021. The Alcohol Use Disorders Identification Test (AUDIT) in the Russian language - a systematic review of validation efforts and application challenges. Subst Abuse Treat Prev Policy, 16(1):76.

Neufeld, M., Rehm, J., Bunova, A., Gil, A., Gornyi, B., Rovira, P., Manthey, J., Yurasova, E., Dolgova, S., Idrisov, B., Moskvicheva, M., Nabiullina, G., Shegaym, O., Zhidkova, I., Ziganshina, Z., Ferreira-Borges, C., the, R.U.S.A.C. & the, R.U.S.A.P.A.B. 2021. Validation of a screening test for alcohol use, the Russian Federation. Bull World Health Organ, 99(7):496-505.

O'Donnell, A., Schulte, B., Manthey, J., Schmidt, C.S., Piazza, M., Chavez, I.B., Natera, G., Aguilar, N.B., Hernandez, G.Y.S., Mejia-Trujillo, J., Perez-Gomez, A., Gual, A., de Vries, H., Solovei, A., Kokole, D., Kaner, E., Kilian, C., Rehm, J., Anderson, P. & Jane-Llopis, E. 2021. Primary care-based screening and management of depression amongst heavy drinking patients: Interim secondary outcomes of a three-country quasi-experimental study in Latin America. PLoS One, 16(8):e0255594.

Patra, J., Buckley, C., Kerr, W.C., Brennan, A., Purshouse, R.C. & Rehm, J. 2021. Impact of body mass and alcohol consumption on all-cause and liver mortality in 240 000 adults in the United States. Drug Alcohol Rev.

Popova, S., Dozet, D., O'Hanlon, G., Temple, V., Rehm, J. 2021. Maternal alcohol use, adverse neonatal outcomes and pregnancy complications in British Columbia, Canada: a population-based study. BMC Pregnancy Childbirth, 21(1):74.

Popova, S., Temple, V., Dozet, D., O'Hanlon, G., Toews, C. & Rehm, J. 2021. Health, social and legal outcomes of individuals with diagnosed or at risk for fetal alcohol spectrum disorder: Canadian example. Drug Alcohol Depend, 219:108487.

Probst, C., Elton-Marshall, T., Imtiaz, S., Patte, K.A., Rehm, J., Sornpaisarn, B. & Leatherdale, S.T. 2021. A supportive school environment may reduce the risk of non-medical prescription opioid use due to impaired mental health among students. Eur Child Adolesc Psychiatry, 30(2):293-301.

Rumgay, H., Shield, K., Charvat, H., Ferrari, P., Sornpaisarn, B., Obot, I., Islami, F., Lemmens, V., Rehm, J. & Soerjomataram, I. 2021. Global burden of cancer in 2020 attributable to alcohol consumption: a population-based study. Lancet Oncol, 22(8):1071-1080.

Russell, C., Ali, F., Nafeh, F., Rehm, J., LeBlanc, S. & Elton-Marshall, T. 2021. Identifying the impacts of the COVID-19 pandemic on service access for people who use drugs (PWUD): A national qualitative study. Journal of Substance Abuse Treatment, 129.

Scherrer, B., Guiraud, J., Addolorato, G., Aubin, H.J., de Bejczy, A., Benyamina, A., van den Brink, W., Caputo, F., Dematteis, M., Goudriaan, A.E., Gual, A., Kiefer, F., Leggio, L., Lesch, O.M., Maremmani, I., Nutt, D.J., Paille, F., Perney, P., Poulnais, R., Raffaillac, Q., Rehm, J., Rolland, B., Simon, N., Soderpalm, B., Sommer, W.H., Walter, H. & Spanagel, R. 2021. Baseline severity and the prediction of placebo response in clinical trials for alcohol dependence: A meta-regression analysis to develop an enrichment strategy. Alcohol Clin Exp Res, 45(9):1722-1734.

Schmidt, R.A., Genois, R., Jin, J., Vigo, D., Rehm, J. & Rush, B. 2021. The early impact of COVID-19 on the incidence, prevalence, and severity of alcohol use and other drugs: A systematic review. Drug Alcohol Depend, 228:109065.

Selmo, P., Knaevelsrud, C., Mohamad, N. & Rehm, J. 2021. Prevalence and predictors of psychopathology in the war-afflicted Syrian population. Transcult Psychiatry, 58(2):226-238.

Shield, K.D. & Rehm, J. 2021. Societal development and the alcohol-attributable burden of disease. Addiction.

Sohi, I., Franklin, A., Chrystoja, B., Wettlaufer, A., Rehm, J. & Shield, K. 2021. The Global Impact of Alcohol Consumption on Premature Mortality and Health in 2016. Nutrients, 13(9).

Sornpaisarn, B., Sornpaisarn, S. & Rehm, J. 2021. The association between the time of alcohol drinking and injury risk in Thailand: a cross-sectional emergency department study. Subst Abuse Treat Prev Policy, 16(1):28.

Štelemėkas, M., Manthey, J., Badaras, R., Casswell, S., Ferreira-Borges, C., Kalėdienė, R., Lange, S., Neufeld, M., Petkevičienė, J., Radišauskas, R., Room, R., Telksnys, T., Zurlytė, I. & Rehm, J. 2021. Alcohol control policy measures and all-cause mortality in Lithuania: an interrupted time-series analysis. Addiction.

Tran, A., Manthey, J., Lange, S., Jiang, H., Stelemekas, M., Liutkute-Gumarov, V., Mesceriakova-Veliuliene, O., Petkeviciene, J., Radisauskas, R., Telksnys, T. & Rehm, J. 2021. Alcohol control policies add to secular trends in all-cause mortality rates in young adults. Sci Rep, 11(1):15127.

Wickens, C.M., Mann, R.E., Brands, B., Stoduto, G., Matheson, J., Sayer, G., Burston, J., Pan, J.F., Di Ciano, P., George, T.P., Rehm, J., Kenney, C., Soule, D., Huestis, M.A. & Le Foll, B. 2021. Influence of personality on acute smoked cannabis effects on simulated driving. Exp Clin Psychopharmacol.

Wright, M., Wickens, C.M., Di Ciano, P., Sproule, B., Fares, A., Matheson, J., Mann, R.E., Rehm, J., Shuper, P.A., George, T.P., Huestis, M.A., Stoduto, G., Le Foll, B. & Brands, B. 2021. Sex differences in the acute pharmacological and subjective effects of smoked cannabis combined with alcohol in young adults. Psychology of Addictive Behaviors, 35(5):536-552.